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Antifreeze Polypeptide (AFP) (HPLC-6), Winter Flounder

CAS No. 122604-16-4

Antifreeze Polypeptide (AFP) (HPLC-6), Winter Flounder( ——— )

Catalog No. M42055 CAS No. 122604-16-4

Antifreeze Polypeptide 6 (winter flounder) is the component 6 of the winter flounder's antifreeze polypeptides. Antifreeze Polypeptide 6 (winter flounder) lowers the plasma freezing point by arresting the growth of ice nuclei.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Antifreeze Polypeptide (AFP) (HPLC-6), Winter Flounder
  • Note
    Research use only, not for human use.
  • Brief Description
    Antifreeze Polypeptide 6 (winter flounder) is the component 6 of the winter flounder's antifreeze polypeptides. Antifreeze Polypeptide 6 (winter flounder) lowers the plasma freezing point by arresting the growth of ice nuclei.
  • Description
    Antifreeze Polypeptide 6 (winter flounder) is the component 6 of the winter flounder's antifreeze polypeptides. Antifreeze Polypeptide 6 (winter flounder) lowers the plasma freezing point by arresting the growth of ice nuclei.
  • In Vitro
    Antifreeze Polypeptide 6 (winter flounder) inhibits the growth of ice crystals by hydrogen bonding of Thr, Asn, and Asp side chains in a specific pattern to the hexagonal bipyramidal planes of ice. This mode of binding is unidirectional, maximizing opportunities for packing of AFPs on the ice surface, and that ice crystal growth inhibition occurs by a two-step mechanism involving hydrogen bonding and hydrophobic interpeptide interactions.
  • In Vivo
    ———
  • Synonyms
    ———
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ———
  • Research Area
    ———
  • Indication
    ———

Chemical Information

  • CAS Number
    122604-16-4
  • Formula Weight
    3242.53
  • Molecular Formula
    C133H225N43O51
  • Purity
    >98% (HPLC)
  • Solubility
    H2O : 45.45 mg/mL (14.02 mM; adjust pH to 1 with 1 M HCL)
  • SMILES
    ———
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Wen D, et al. A model for binding of an antifreeze polypeptide to ice. Biophys J. 1992 Dec;63(6):1659-62.?
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